➕ Reduce bloating
➕ Improve nutrition
➕ Simplify visits
FODZYME®‘s enzyme blend breaks down FODMAPs before they can cause symptoms, supporting nutritional diversity, dietary flexibility, symptom relief and enhanced quality of life for patients.
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FODZYME® FODMAP-targeted enzymes provide digestive relief — without dietary restriction
10,000+
Providers trust FODZYME®
90%
of 3g fructan broken down within 30 min1
70%
Report decreased bloating after 4 weeks2
Effective Relief from FODMAP-Related Symptoms:
✔️ Bloating and Gas
✔️ Diarrhea
✔️ Abdominal Discomfort
✔️ Constipation
ADVISORS
With a team of experts in medicine, nutrition, and biotechnology, we have developed proprietary digestive enzymes. FODZYME®’s novel fructan hydrolase is the only enzyme available that can break down fructans, the most common FODMAP trigger in IBS.
Dr. William Chey
Chief, Division of Gastroenterology & Hepatology at Michigan Medicine
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Dr. Thomas Wallach
Chief, Division of Pediatric Gastroenterology at SUNY Downstate
WHY FODZYME®?
Your patients have tried everything to find relief —
elimination diets, complex protocols, remedies from online influencers. Controlling common digestive issues shouldn’t be this complex, or restrictive.
With FODZYME®, offer your patients an easy, simple way to manage bloating, gas, abdominal discomfort, diarrhea and constipation. No dietary change required.
WHICH PATIENTS BENEFIT?
Uninterested in or frustrated with the low FODMAP diet
With anxiety or fear around gut triggers and dietary expansion
With a history of or at risk for disordered eating
Already on a restrictive diet or contraindicated for one
How FODZYME® Works
FODZYME®'s unique blend features a novel fructan hydrolase, plus alpha-galactosidase and lactase. Fructan hydrolase is the only enzyme available that can break down fructans, the most common FODMAP trigger in IBS. FODZYME® is available over the counter.
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Fructan hydrolase
FODMAP substrate: Fructans including fructo-oligosaccharides (FOS) and inulin
Common foods: Artichoke, asparagus, bread, Brussels sprouts, garlic, leek, onion, shallot, wheat products
Alpha-galactosidase
FODMAP substrate: Galacto-oligosaccharides (GOS/galactans)
Common foods: Beans, beets, cashews, chickpeas, hummus, lentils, pistachio, silken tofu, soybeans
Lactase
FODMAP substrate: Lactose
Common foods: Cottage cheese, buttermilk, ice cream, kefir, milk, ricotta, soft cheese, yogurt
In development are additional enzymes to address polyols, like mannitol and sorbitol, found in foods such as apple, cauliflower, celery, mushroom and stone fruits.
FODZYME® helps patients enjoy many healthy, nutritious and delicious foods — without worry of symptoms
** FODZYME® significantly reduces fructan (a FODMAP) in wheat, barley and rye products, not gluten. Fructan is often the real trigger in individuals with non-celiac gluten sensitivity.
FREE Resources for Healthcare Providers
The Low FODMAP Diet & Digestive Enzymes
A patient-friendly, easy-to-use one pager about the low FODMAP diet and how digestive enzymes like FODZYME® support FODMAP tolerance
FODZYME® One Pager for Clinicians
A brief overview on how FODZYME® works to break down FODMAPs, the research behind the enzyme blend and which patients benefit
Publication List on Enzyme Research
A summary on the research literature supporting use of FODMAP-targeting digestive enzymes, such as a FODZYME®, for IBS
Go beyond the low FODMAP diet with a new standard of care
The low FODMAP diet is complex and burdensome. If used, dietary elimination should be temporary. Plus, patients are looking for solutions that provide relief today.
Put an end to restrictive diets and an endless cycle of inconclusive visits with FODZYME® digestive enzymes. FODZYME® seamlessly integrates into your patients' current diet and lifestyle behaviors, allowing them to get back to their busy lives and streamlining your care process.
Evidence-based
Digestive enzymes are a widely recommended safe and effective intervention for patients with FODMAP intolerances
Easy to use
Simply sprinkle on meals. FODZYME®'s enzymes break down the FODMAPs fructan, GOS and lactose upon contact, before they can trigger symptoms
High-impact
Up to 80% of patients with IBS suffer from FODMAP intolerances, yet many are uninterested or contraindicated for diet restriction and need alternative solutions
Top Healthcare Providers Recommend FODZYME®
Gastroenterologists ● Registered Dietitians ● Nurses ● Primary Care Physicians ● Physician Assistants
"Not only do I suggest FODZYME® as a tool for my clients to boost food variety and reduce 'FODMAP Fatigue.' I also use it to manage my own digestive distress to enjoy the foods I love!"
"For my patients struggling with fodmap sensitivities, especially to fructans, GOS and lactose, FODZYME® has been a god-send.
Anecdotally, patients have described being about to eat outside the home with significantly more ease and enjoyment, and has allowed some to start cooking with onion and garlic again."
"The best compliment I get from my patients is when they finally have freedom to eat what they love. With FODZYME®, my patients have been enjoying high-fiber meals that are painless and make them feel good.”
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Join the thousands of providers who trust FODZYME®
Help your patients try FODZYME® risk-free with free samples, coupons and educational resources.
Eliminate the need for restrictive diets, complex grocery lists and special meal requests.
Your patients will thank you — we guarantee it.
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1. Kenny Castro Ochoa, Samant S, Liu A, et al. In Vitro Efficacy of Targeted Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Enzymatic Digestion in a High-Fidelity Simulated Gastrointestinal Environment. Gastro Hep Advances. 2022;2(3):283-290. doi:https://doi.org/10.1016/j.gastha.2022.10.011
2. Kaye AJ. Fodzyme at Its Finest: A Case Series Exploring a New Option for IBS Patients. Presented at: The American College of Gastroenterology; October 2024; Philadelphia, PA. Poster P4059.